Supplementary study guide: Nervous, Musculoskeletal, Senses and Endocrine systems
Extra-class tutor: Teboho Mpholo (Mr.), Cre8Learn Institute
Supports: Botho University Health Information Management programme
Reference text: Tortora & Derrickson, 14th Edition
Almost every medical term is built from a prefix (start), a root (core meaning) and a suffix (end). Learn the parts and you can decode words you have never seen.
| Prefixes | Roots | Suffixes |
|---|---|---|
| a-/an- without brady- slow tachy- fast hyper- above, excess hypo- below, deficient dys- difficult, abnormal poly- many peri- around endo- within hemi- half |
neur(o) nerve encephal(o) brain cerebr(o) cerebrum oste(o) bone arthr(o) joint my(o) muscle ophthalm(o), ocul(o) eye ot(o) ear thyr(o) thyroid gluc(o), glyc(o) sugar |
-itis inflammation -pathy disease -algia pain -emia blood condition -osis abnormal condition -penia deficiency -plegia paralysis -paresis weakness -ectomy removal -otomy cutting into -plasty surgical repair -scopy viewing |
Decode hemiplegia, polyneuropathy and arthroplasty.
Answer: hemiplegia = half + paralysis (paralysis of one side of the body); polyneuropathy = many + nerve + disease (disease affecting many nerves); arthroplasty = joint + surgical repair.
The body's electrical wiring, divided into the Central Nervous System (CNS) (brain and spinal cord) and the Peripheral Nervous System (PNS) (nerves branching out, including 12 pairs of cranial nerves and 31 pairs of spinal nerves).
| Structure | Main role |
|---|---|
| Cerebrum | Thought, memory, voluntary movement, sensation. Lobes: frontal, parietal, temporal, occipital |
| Cerebellum | Coordination, balance, smooth movement |
| Brainstem | Breathing, heart rate, consciousness |
| Hypothalamus | Body temperature, hunger, thirst; controls the pituitary gland |
| Spinal cord | Carries signals between brain and body; reflex arcs |
| Meninges | Three protective membranes (dura mater, arachnoid mater, pia mater) around brain and cord |
| Neuron | Dendrites receive signals; the axon sends them; the myelin sheath speeds conduction |
| Autonomic system | Involuntary control. Sympathetic is fight or flight; parasympathetic is rest and digest |
Scenario: "Meningitis due to Streptococcus pneumoniae." Which structure is inflamed, and why does the organism matter?
Answer: The meninges. ICD-10 classifies bacterial meningitis by cause, so the organism determines the code and supports accurate statistics.
Structure, support and movement. The adult skeleton has 206 bones: the axial skeleton (skull, spine, ribs, sternum) and the appendicular skeleton (limbs, shoulder and pelvic girdles).
| Structure | Main role |
|---|---|
| Osteoblasts / osteoclasts | Osteoblasts build bone; osteoclasts break it down. They must stay in balance |
| Fibrous joints | Immovable (skull sutures) |
| Cartilaginous joints | Slightly movable (between vertebrae) |
| Synovial joints | Freely movable (knee, shoulder, hip) |
| Skeletal muscle | Voluntary, striated; moves bones via tendons |
| Cardiac muscle | Involuntary, striated; found only in the heart |
| Smooth muscle | Involuntary, non-striated; walls of organs and vessels |
| Ligament / tendon | Ligaments join bone to bone; tendons join muscle to bone |
Scenario: "Fell off a ladder. Right femur is broken and protruding through the skin." What three details do you extract, and what else do you confirm?
Answer: The bone (femur), laterality (right) and fracture type (open, because it protrudes through skin). Confirm the encounter type (initial or subsequent). If anything is missing, query.
| Structure | Main role |
|---|---|
| Cornea, lens | Focus light onto the retina (the cornea does most of the focusing) |
| Iris, pupil | Control how much light enters |
| Retina | Rods (dim light, black and white) and cones (colour); signals leave via the optic nerve |
| Outer ear | Collects sound and channels it to the eardrum |
| Middle ear | Eardrum and three tiny bones (ossicles) pass vibrations inward |
| Inner ear | Cochlea for hearing; semicircular canals and vestibule for balance |
| Taste, smell, touch | Taste buds and olfactory receptors detect chemicals; skin receptors detect touch, pressure, temperature and pain |
Scenario: "Difficulty hearing high-pitched sounds, likely due to ageing." What must the provider document before you assign a type of hearing loss, and what if it is missing?
Answer: The type and cause (e.g. sensorineural hearing loss due to presbycusis). You cannot work it out from symptoms, so you query. Note also the word "likely": uncertain terms are treated differently in inpatient and outpatient coding.
Scenario: One chart says "clouding of the lens"; another says "elevated intraocular pressure." What does each point to, and what do you do for the second?
Answer: The first is a cataract. The second is a finding, not a diagnosis (ocular hypertension or glaucoma). Code what the provider documents and query if no diagnosis is stated.
Hormones and glands. Chemical messengers regulate metabolism, growth, reproduction and mood, largely through negative feedback: when a hormone level rises too high, the body signals the gland to reduce output.
| Gland | Key hormones and roles |
|---|---|
| Hypothalamus | Links nervous and endocrine systems; controls the pituitary |
| Pituitary | The "master gland": growth hormone, ADH, TSH and others |
| Thyroid | T3 and T4 set metabolic rate |
| Parathyroids | Parathyroid hormone raises blood calcium |
| Adrenals | Cortisol (stress, glucose), aldosterone (salt and water), adrenaline |
| Pancreas | Insulin lowers blood glucose; glucagon raises it |
| Gonads | Oestrogen and progesterone (ovaries); testosterone (testes) |
| Pineal | Melatonin, sleep-wake rhythm |
Scenario: "Type 2 diabetes mellitus. Patient reports numbness and tingling in both feet." Can you code diabetic neuropathy?
Answer: No. Numbness and tingling are symptoms, not a diagnosis. Query the physician. Once "diabetic neuropathy" is documented, the combination code applies.
1. Break down osteoarthritis, and say whether it is mainly inflammatory.
Osteo (bone) + arthr (joint) + itis (inflammation). Despite the suffix, OA is mainly degenerative, unlike RA.
2. What does hypothyroidism mean from its parts?
Hypo (below, deficient) + thyroid + ism (condition): an underactive thyroid.
3. What is the difference between a ligament and a tendon?
Ligaments join bone to bone; tendons join muscle to bone.
4. Which part of the brain coordinates balance and smooth movement?
The cerebellum.
5. What is the difference between osteoblasts and osteoclasts?
Osteoblasts build bone; osteoclasts break it down. Osteoporosis results when breakdown outpaces building.
6. Which hormone raises blood glucose, and which lowers it?
Glucagon raises it; insulin lowers it.
7. A chart says "haemorrhagic CVA." What is happening?
A blood vessel has ruptured and bleeding occurs in or around the brain, unlike an ischaemic CVA, where a blockage cuts off blood flow.
8. Why must you not assign glaucoma from "elevated intraocular pressure"?
Raised pressure is a finding, not a diagnosis. It may be ocular hypertension or glaucoma (which can even occur with normal pressure). The provider must document it; otherwise you query.
9. A fracture is not documented as open or closed. How is it classified in ICD-10-CM?
As closed, by convention. If the wording seems incomplete, check the full record.
10. A chart says "suspected multiple sclerosis" on an outpatient visit. Can you code MS?
Generally no. Outpatient guidelines say not to code uncertain diagnoses such as "suspected" or "probable"; code the documented signs and symptoms instead. Inpatient rules differ, so check your guidelines.
| Abbreviation | Meaning | Abbreviation | Meaning |
|---|---|---|---|
| CNS / PNS | Central / peripheral nervous system | DM | Diabetes mellitus |
| CVA | Cerebrovascular accident | DKA | Diabetic ketoacidosis |
| TIA | Transient ischaemic attack | T1DM / T2DM | Type 1 / type 2 diabetes |
| MS | Multiple sclerosis | TSH | Thyroid-stimulating hormone |
| OA / RA | Osteoarthritis / rheumatoid arthritis | ADH | Antidiuretic hormone |
| ORIF | Open reduction, internal fixation | IOP | Intraocular pressure |
| AMD | Age-related macular degeneration | ICD-10-CM | Diagnosis classification (clinical modification) |